About the Company:

Tentarix Biotherapeutics is an exciting company with a game-changing technology platform that allows for the discovery of next generation, multi-specific investigational drugs, called Tentacles, to address limitations of existing cancer, autoimmune and other disease therapies. 

We are led by a seasoned executive team with proven expertise in the field of multi-specific drug discovery. We are committed to hiring and retaining highly qualified and motivated team members who are passionate about making a difference for patients in the modern drug discovery landscape with our ground-breaking technology. 

Tentarix team members are creative, hands-on, self-directed, and display excellent communication skills. They also exhibit a high level of integrity, resiliency, and a determination to contribute to the success of the company. We offer autonomy, flexibility, a modern culture, and the best tools to ensure the success of our individuals and collectively.

Role:

The Senior Research Associate will be primarily responsible for in vivo studies evaluating the activity of engineered protein therapeutics. Additional responsibilities include the ex vivo assessments of pharmacokinetic and pharmacodynamic aspects of biotherapeutics. There will also be an opportunity to contribute to in vitro studies for evaluating the activity of engineered protein therapeutics.

Responsibilities:

• Responsible for the development and execution of a range of Pharmacology studies including cell-based screening assays, immune cell bioassays, PK/PD assays and disease models for immuno-oncology, autoimmune and other in vivo immune-related disease models such as Tumor growth inhibition studies in humanized NSG tumor mice and autoimmune models
• Independently design and execute experiments, analyze results, make presentations, and present data in group meetings
• Maintain a meticulous record of protocols, data, and results

 Qualifications and Skills:

• M.S/B.S./B.A. with 2-6+ years of industry experience in the field of immuno-oncology, autoimmune diseases, or other inflammatory diseases
• Experience with animal handling and basic in vivo procedures of dosing, such as injections with various routes (s.c., i.p., i.v.), bleeding (cheek bleed, Retro Orbital), tumor measurement and collection of various organs for necroscopy for toxicology studies is required
• Experience with in vivo cancer or autoimmune disease models is also required
• Experience with cell culture including the culture of immune cells and tumor cells is desired
• Technical experience in the development and execution of ELISAs, MSD, gene expression analysis, flow-cytometry, in vitro and ex vivo immunology assays, and/or in vivo pharmacodynamics and pharmacokinetic assays is a plus, but candidate can also be trained
• Goal oriented, organized, and capable of multitasking.
• Thrive in a cross functional team environment
• Excellent verbal and written communication skills

 Our employees are the Company’s most valuable asset, so we offer attractive compensation and benefits packages to retain the best in the field. Tentarix is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability, or veteran status. 

The wage range for this role takes into account the wide range of factors that are considered in making compensation decisions including but not limited to skill sets, experience, training, licensure, certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Tentarix, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current range is $81,000 – $100,000 + bonus target + benefits + equity.

Tentarix Biotherapeutics, Inc. also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. We are an E-Verify employer.