About the Company:

Tentarix Biotherapeutics is an exciting company with a game-changing technology platform that allows for the discovery of next generation, multi-specific investigational drugs, called Tentacles, to address limitations of existing cancer, autoimmune and other disease therapies. 

We are led by a seasoned executive team with proven expertise in the field of multi-specific drug discovery. We are committed to hiring and retaining highly qualified and motivated team members who are passionate about making a difference for patients in the modern drug discovery landscape with our ground-breaking technology. 

Tentarix team members are creative, hands-on, self-directed, and display excellent communication skills. They also exhibit a high level of integrity, resiliency, and a determination to contribute to the success of the company. We offer autonomy, flexibility, a modern culture, and the best tools to ensure the success of our individuals and collectively.

Role:

The Scientist: Biotherapeutics Design, will be responsible for the discovery and engineering of Tentatrix’s multi-specific Tentacles as well as all things related to protein and antigen design. The scientist will be expected to work within a high functioning team of scientists devoted to the generation of antigen binders using our proprietary, stabilized, fully human VH scaffolds and fully human antibodies, the design and production of multi-specifics that target various cellular targets to induce cell-specific immune suppression or immune activation for autoimmunity and immuno-oncology, respectively, and the development of innovative novel methods for protein and multi-specific design and screening.

Responsibilities:

• Participate in all aspects of binder discovery including naïve library design, library screening, and hit characterization
• Participate in the design of antigen or antigen fragments to meet program goals
• Utilize a background in protein design to propose and construct novel multi-specific compounds to achieve project-specific therapeutic goals
• Communicate effectively within the Biotherapeutics Design team and other teams to enhance efficiencies and feedback across our research group

Qualifications and Skills:

• Ph.D. in molecular biophysics or molecular biology with an emphasis on protein design. Post-doctoral experience is preferred, with 2+ years industry experience.
• Experience with one or more high throughput in-vitro discovery or design methodologies including phage display, yeast display, or other techniques
• Experience with protein design and protein biophysical properties including the use of various protein characterization techniques including ELISA, biolayer interferometry (BLI), differential scanning fluorimetry (DSF), or overlapping methods
• Goal oriented, organized, capable of prioritizing across multiple projects, and able to execute to timelines that meet company goals
• A track record of innovation and scientific rigor, strong problem solving and troubleshooting skills, and ability to contribute constructively to discussions.
• Thrive in a cross functional team environment and committed to positively contributing to Tentarix supportive small company culture
• Excellent verbal and written communication skills
• Confident, independent and decisive; proactive and results-oriented with high performance standards
• Hands-on contributor who understands the need for involvement at all levels of activity within a small company environment
• Commitment to exhibiting the highest levels of integrity, ethics and scientific standards

The wage range for this role takes into account the wide range of factors that are considered in making compensation decisions including, but not limited to, skill sets, experience, training, licensure, certifications, and other business and organizational needs. The disclosed range estimate has not been adjusted for the applicable geographic differential associated with the location at which the position may be filled. At Tentarix, it is not typical for an individual to be hired at or near the top of the range for their role and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current range is $130,000 – $145,000 + bonus target + benefits + equity.  

Our employees are the Company’s most valuable asset, so we offer attractive compensation and benefits packages to retain the best in the field. Tentarix is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. 

Tentarix Biotherapeutics, Inc. also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. We are an E-Verify employer.